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dc.contributor.authorBousquet, J. and Devillier, P. and Anto, J.M. and Bewick, M. and Haahtela, T. and Arnavielhe, S. and Bedbrook, A. and Murray, R. and van Eerd, M. and Fonseca, J.A. and Morais Almeida, M. and Todo Bom, A. and Menditto, E. and Passalacqua, G. and Stellato, C. and Triggiani, M. and Ventura, M.T. and Vezzani, G. and Annesi-Maesano, I. and Bourret, R. and Bosse, I. and Caimmi, D. and Cartier, C. and Demoly, P. and Just, J. and Portejoie, F. and Siroux, V. and Viart, F. and Bergmann, K.C. and Keil, T. and Klimek, L. and Mösges, R. and Pfaar, O. and Shamai, S. and Zuberbier, T. and Mullol, J. and Valero, A. and Spranger, O. and Tomazic, P.V. and Kowalski, M.L. and Kuna, P. and Kupczyk, M. and Raciborski, F. and Samolinski, B. and Toppila-Salmi, S.K. and Valovirta, E. and Cruz, A.A. and Sarquis-Serpa, F. and da Silva, J. and Stelmach, R. and Larenas-Linnemann, D. and Rodriguez Gonzalez, M. and Burguete Cabañas, M.T. and Kvedariene, V. and Valiulis, A. and Chavannes, N.H. and Fokkens, W.J. and Ryan, D. and Sheikh, A. and Bachert, C. and Hellings, P.W. and VandenPlas, O. and Ballardini, N. and Kull, I. and Melén, E. and Westman, M. and Wickman, M. and Bindslev-Jensen, C. and Eller, E. and Bosnic-Anticevich, S. and O'Hehir, R.E. and Agache, I. and Bieber, T. and Casale, T. and Gemicioğlu, B. and Ivancevich, J.C. and De Vries, G. and Sorensen, M. and Yorgancioglu, A. and Laune, D. and MACVIA working group
dc.date.accessioned2020-07-02T07:10:12Z
dc.date.available2020-07-02T07:10:12Z
dc.date.issued2018
dc.identifier.citationcited By 27
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85045929487&doi=10.1111%2fall.13448&partnerID=40&md5=226928e44e46ec47dc043259bad3e423
dc.identifier.urihttp://hdl.handle.net/20.500.12481/12075
dc.description.abstractBackground: Multimorbidity in allergic airway diseases is well known, but no data exist about the daily dynamics of symptoms and their impact on work. To better understand this, we aimed to assess the presence and control of daily allergic multimorbidity (asthma, conjunctivitis, rhinitis) and its impact on work productivity using a mobile technology, the Allergy Diary. Methods: We undertook a 1-year prospective observational study in which 4 210 users and 32 585 days were monitored in 19 countries. Five visual analogue scales (VAS) assessed the daily burden of the disease (i.e., global evaluation, nose, eyes, asthma and work). Visual analogue scale levels <20/100 were categorized as “Low” burden and VAS levels ≥50/100 as “High” burden. Results: Visual analogue scales global measured levels assessing the global control of the allergic disease were significantly associated with allergic multimorbidity. Eight hypothesis-driven patterns were defined based on “Low” and “High” VAS levels. There were <0.2% days of Rhinitis Low and Asthma High or Conjunctivitis High patterns. There were 5.9% days with a Rhinitis High—Asthma Low pattern. There were 1.7% days with a Rhinitis High—Asthma High—Conjunctivitis Low pattern. A novel Rhinitis High—Asthma High—Conjunctivitis High pattern was identified in 2.9% days and had the greatest impact on uncontrolled VAS global measured and impaired work productivity. Work productivity was significantly correlated with VAS global measured levels. Conclusions: In a novel approach examining daily symptoms with mobile technology, we found considerable intra-individual variability of allergic multimorbidity including a previously unrecognized extreme pattern of uncontrolled multimorbidity. © 2018 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.
dc.language.isoEnglish
dc.publisherBlackwell Publishing Ltd
dc.titleDaily allergic multimorbidity in rhinitis using mobile technology: A novel concept of the MASK study
dc.typeReview
dc.contributor.departmentMACVIA-France, Contre les MAladies Chroniques pour un VIeillissement Actif en France European Innovation Partnership on Active and Healthy Ageing Reference Site, Montpellier, France; INSERM U 1168, VIMA: Ageing and Chronic Diseases Epidemiological and Public Health Approaches, Villejuif, France; UMR-S 1168, Université Versailles St-Quentin-en-Yvelines, Montigny le Bretonneux, France; Euforea, Brussels, Belgium; Charité, Berlin, Germany; Laboratoire de Pharmacologie Respiratoire UPRES EA220, Pôle des Maladies Respiratoires, Hôpital Foch, Suresnes Université Versailles Saint-Quentin, Suresnes, France; ISGloBAL, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain; IMIM (Hospital del Mar Research Institute), Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; iQ4U Consultants Ltd, London, United Kingdom; Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland; Kyomed, Montpellier, France; MedScript Ltd, Dundalk, Ireland; Peercode DV, Gerdermalsen, Netherlands; Faculdade de Medicina, Center for Health Technology and Services Research- CINTESIS, MEDIDA, Lda, Universidade do Porto, Porto, Portugal; Allergy and Clinical Immunology Department, Hospital CUF-Descobertas, Lisboa, Portugal; Imunoalergologia, Faculty of Medicine, Centro Hospitalar Universitário de Coimbra, University of Coimbra, Coimbra, Portugal; CIRFF, Center of Pharmacoeconomics, University of Naples Federico II, Naples, Italy; Allergy and Respiratory Diseases, Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy; Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Salerno, Italy; Unit of Geriatric Immunoallergology, University of Bari Medical School, Bari, Italy; Pulmonary Unit, Department of Medical Specialties, Arcispedale SMaria Nuova/IRCCS, AUSL di Reggio Emilia, Reggio Emilia, Italy; Epidemiology of Allergic and Respiratory Diseases, Department Institute Pierre Louis of Epidemiology and Public Health, INSERM, Medical School Saint Antoine, UPMC Sorbonne Universités, Paris, France; Centre Hospitalier, Valenciennes, France; Allergist, La Rochelle, France; CHRU de Montpellier, UMR-S 1136, IPLESP, Equipe EPAR, UPMC Paris 06, Sorbonne Universités, Paris, France; ASA - Advanced Solutions Accelerator, Clapiers, France; Allergology Department, Centre de l'Asthme et des Allergies Hôpital d'Enfants Armand-Trousseau (APHP), Paris, France; UMR_S 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Equipe EPAR, UPMC Univ Paris 06, Sorbonne Universités, Paris, France; INSERM, IAB, U 1209, Team of Environmental Epidemiology applied to Reproduction and Respiratory Health, Université Grenoble Alpes, Université Joseph Fourier, Grenoble, France; Department of Dermatology and Allergy, Comprehensive Allergy-Centre-Charité, Charité - Universitätsmedizin Berlin, Berlin, Germany; Global Allergy and Asthma European Network (GA2LEN), Berlin, Germany; Institute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Berlin, Germany; Institute for Clinical Epidemiology and Biometry, University of Wuerzburg, Wuerzburg, Germany; Center for Rhinology and Allergology, Wiesbaden, Germany; Department of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty Mannheim, Universitätsmedizin Mannheim, Heidelberg University, Mannheim, Germany; CRI-Clinical Research International-Ltd, Hamburg, Germany; Medical Faculty, Institute of Medical Statistics, and Computational Biology, University of Cologne, Cologne, Germany; Rhinology Unit & Smell Clínic, ENT Department, Hospital Clinic, University of Barcelona, Barcelona, Spain; Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, CIBERES, University of Barcelona, Barcelona, Spain; Global Allergy and Asthma Platform GAAPP, Vienna, Austria; Department of ENT, Medical University of Graz, Graz, Austria; Department of Immunology, Rheumatology and Allergy, HARC, Medical University of Lodz, Lodz, Poland; Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland; Department of Prevention of Envinronmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland; Department of Lung Diseases and Clinical Immunology, University of Turku, Turku, Finland; Terveystalo Allergy Clinic, Turku, Finland; ProAR – Nucleo de Excelencia em Asma, Federal University of Bahia, Salvador, Brazil; GARD Executive Committee, Salvador, Brazil; Asthma Reference Center, Escola Superior de Ciencias da Santa Casa de Misericordia de VitoriaEsperito Santo, Brazil; Nucleo de Alergia, Hospital Universitario Polydoro Ernani de Sao Thiago, Federal University of Santa Catarina (HU-UFSC), Florioanopolis, Brazil; Pulmonary Division, Heart Institute (InCor), Hospital da Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil; Center of Excellence in Asthma and Allergy, Hospital Médica Sur, México City, Mexico; Pediatric Allergy and Clinical Immunology, Hospital Angeles Pedregal, Mexico City, Mexico; Centro Médico Zambrano Hellion, Monterrey, Mexico; Departement of Pathology, Forensic Medicine and Pharmacology, Faculty of Medicine, Clinic of Infecious, Chest Diseases, Dermatology and Allergology, Institute of Biomedical Sciences, Vilnius University, Vilnius, Lithuania; Clinic of Infecious, Chest Diseases, Dermatology and Allergology, Institute of Clinical Medicine, Vilnius, Lithuania; Department of Public Health, Clinic of Children's Diseases, Institute of Health Sciences, Vilnius University Institute of Clinical Medicine, Vilnius, Lithuania; European Academy of Paediatrics (EAP/UEMS-SP), Brussels, Belgium; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, Netherlands; Department of Otorhinolaryngology, Academic Medical Centre, Amsterdam, Netherlands; Allergy and Respiratory Research Group, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom; Asthma UK Centre for Applied Research, Centre of Medical Informatics, Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, Edinburgh, United Kingdom; ENT Department, Upper Airways Research Laboratory, Ghent University Hospital, Ghent, Belgium; Department of Otorhinolaryngology, University Hospitals Leuven, Leuven, Belgium; Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; Department of Chest Medicine, Centre Hospitalier Universitaire UCL Namur, Université Catholique de Louvain, Yvoir, Belgium; Centre for Clinical Research Sörmland, Uppsala University, Eskilstuna, Sweden; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden; Sachs’ Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Medicine Solna, Immunology and Allergy Unit, Karolinska Institutet, Stockholm, Sweden; Department of ENT Diseases, Karolinska University Hospital, Stockholm, Sweden; Department of Dermatology and Allergy Centre, Odense Research Center for Anaphylaxis (ORCA), Odense University Hospital, Odense, Denmark; Woolcock Institute of Medical Research, Sydney Local Health District, University of Sydney, Glebe, NSW, Australia; Department of Allergy, Immunology and Respiratory Medicine, Alfred Hospital and Central Clinical School, Monash University, Melbourne, VIC, Australia; Department of Immunology, Monash University, Melbourne, VIC, Australia; Transylvania University, Brasov, Romania; Department of Dermatology and Allergy, Rheinische Friedrich-Wilhelms-University Bonn, Bonn, Germany; Division of Allergy/Immunology, University of South Florida, Tampa, FL, United States; Department of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey; Servicio de Alergia e Immunologia, Clinica Santa Isabel, Buenos Aires, Argentina; Department of Paediatric and Adolescent Medicine, University Hospital of North Norway, Tromsø, Norway; Department of Clinical Medicine, Paediatric Research Group, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, Norway; Department of Pulmonology, Celal Bayar University, Manisa, Turkey; GARD Executive Committee, Manisa, Turkey
dc.identifier.DOI-ID10.1111/all.13448
dc.identifier.volume73
dc.identifier.pages1622-1631


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