Effects of Radioiodine (I131) on Mitotic Chromosomes of Root Meristem Cells of Vicia faba L. and Numerical Evaluation

Abstract

In this study Cytotoxic effects of radioiodine (I131) which is a radionuclide used for the diagnosis andtreatment of thyroid cancers and hyperthyroidism on mitotic chromosomes of root tips meristematic cells of fava bean [Viciafaba L. (Fabaceae)] were investigated. Seeds treated with radioiodine (I131) for 24, 48, 96 hours and 16 days were germinated.The root tips were taken and prepared for microscopic studies. Radioiodine (I131) caused chromosomal abnormalities aschromosome adherence, chromosome breaks, ring chromosome, chromatin bridge in V. faba L. root tip cells. The most commontype of observed abnormalities was fish bone chromosome adherence, ring and C chromosome and chromosome dispersion. As aresult of this study, it was determined that radioiodine (I131) had a mitodepressive effect on mitosis and harmful effects on V. fabaL. root tip cells. The data obtained were evaluated numerically and statistical analysis was performed.