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dc.contributor.authorBerrin ER Pınar Yıldız GÜLHAN Özlem ATAOĞLU Canan GÜNDÜZ Aycan YÜKSEL Hüseyin ARIKAN Tuğba ŞİŞMANLAR EYÜBOĞLU Nagehan EMİRALİOĞLU Tuğba RAMASLI GÜRSOY İrem ŞERİFOĞLU Zehra Nur TÖREYİN Selin ÇAKMAKÇI Tuba ÇİFTÇİ KÜSBECİ Oğuz KARCIOĞLU Merve ERÇELİK Demet POLAT İlknur KAYA Tuğba Aslı ÖNYILMAZ Asena AYDIN Deniz KIZILIRMAK Aslıhan Banu ER Mukaddes KILINÇ Fatma Esra GÜNAYDIN Selçuk GÜRZ Selen KARAOĞLANOĞLU Selma ÇELİK Hüseyin TOPTAY Ümran Özden SERTÇELİK Metin AKGÜN Feride MARİM Bilge YILMAZ KARA Dilek KARADOĞAN Dorina ESENDAĞLI Elif DEVELİ Hilal ÖZAKINCI Fatma TOKGÖZ AKYIL
dc.date.accessioned2023-03-03T09:48:21Z
dc.date.available2023-03-03T09:48:21Z
dc.date.issued2020
dc.identifier.urihttp://hdl.handle.net/20.500.12481/18383
dc.description.abstractThe novel coronavirus pandemic poses a major global threat to public health. Our knowledge concerning every aspect of COVID-19is evolving rapidly, given the increasing data from all over the world. In this narrative review, the Turkish Thoracic Society Early CareerTaskforce members aimed to provide a summary on recent literature regarding epidemiology, clinical findings, diagnosis, treatment,prevention, and control of COVID-19. Studies revealed that the genetic sequence of the novel coronavirus showed significant identityto SARS-CoV and MERS-CoV. Angiotensin-converting enzyme 2 receptor is an important target of the SARS-CoV-2 while entering anorganism. Smokers were more likely to develop the disease and have a higher risk for ICU admission. The mean incubation periodwas 6.4 days, whereas asymptomatic transmission was reported up to 25 days after infection. Fever and cough were the most commonsymptoms, and cardiovascular diseases and hypertension were reported to be the most common comorbidities among patients. Clinicalmanifestations range from asymptomatic and mild disease to severe acute respiratory distress syndrome. Several patients showed typicalsymptoms and radiological changes with negative RT-PCR but positive IgG and IgM antibodies. Although radiological findings may vary,bilateral, peripherally distributed, ground-glass opacities were typical of COVID-19. Poor prognosis was associated with older age, higherSequential Organ Failure Assessment score, and high D-dimer level. Chloroquine was found to be effective in reducing viral replicationin vitro. Likewise, protease inhibitors, including lopinavir/ritonavir, favipiravir, and nucleoside analogue remdesivir were proposed to bethe potential drug candidates in COVID-19 management. Despite these efforts, we still have much to learn regarding the transmission,treatment, and prevention of COVID-19
dc.titleWhat We Learned about COVID-19 So Far? Notes from Underground
dc.identifier.volume21
dc.identifier.startpage185
dc.identifier.endpage192
dc.identifier.issn/e-issn2149-2530


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    TR - Dizin İndeksli Yayınlar Koleksiyonu

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