dc.contributor.author | Gürol Şahin ULUTAŞ;AYLİN ÖZGEN ALPAYDIN;FATMA TANELİ;Cemile ÇETİNKAYA;Cevval ULMAN;YEŞİM GÜVENÇ DEMİRAĞCI;GÖNÜL DİNÇ HORASAN;Ayşın Şakar COŞKUN | |
dc.date.accessioned | 2020-06-30T10:26:37Z | |
dc.date.available | 2020-06-30T10:26:37Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | 0 | |
dc.identifier.uri | https://app.trdizin.gov.tr/publication/paper/detail/TWpJM05EWTFOUT09 | |
dc.identifier.uri | http://hdl.handle.net/20.500.12481/2154 | |
dc.description.abstract | as well as the relationship of these cells with pulmonary functions in chronic obstructive pulmonary disease (COPD) patients.MATerIAL ANd MeTHods: Forty COPD patients and 40 healthy volunteers were included. Participants were analysed in four groups according to their smoking status. Peripheral blood CD4+ and CD8+ T cells and monocyte TLR-2 expression were measured by flow cytometry in the whole study population.resULTs: No significant difference was observed in TLR-2 expression, number of CD4+ and CD8+ T cells, and CD4+/CD8+ T cell ratio between the study groups. CD4+/CD8+ T cell ratio and FEV1/FVC were found to have a mild positive correlation (r=0.295, p=0.022). A mild negative correlation was observed between smoking intensity and CD4+/CD8+ T cell ratio (r=-0.274, p=0.034).CoNCLUsIoN: We demonstrated a mild correlation between pulmonary functions and peripheral blood CD4+/CD8+ T cell ratio. However, we did not find a significant difference in TLR-2 expression of CD14+ monocytes in patients with airway obstruction. | |
dc.language.iso | eng | |
dc.title | Toll-Like Receptor 2 Expression and Peripheral Blood CD4+/CD8+ T Cell Ratio in COPD | |
dc.type | RESEARCH | |
dc.contributor.department | Tanımlanmamış Kurum;DOKUZ EYLÜL ÜNİVERSİTESİ;CELÂL BAYAR ÜNİVERSİTESİ;CELÂL BAYAR ÜNİVERSİTESİ;CELÂL BAYAR ÜNİVERSİTESİ;CELÂL BAYAR ÜNİVERSİTESİ;CELÂL BAYAR ÜNİVERSİTESİ;CELÂL BAYAR ÜNİVERSİTESİ | |
dc.identifier.nameOfPublishedMaterial | Türk Toraks Dergisi | |
dc.identifier.volume | 15 | |
dc.identifier.issue | 3 | |
dc.identifier.startpage | 106 | |
dc.identifier.endpage | 111 | |
dc.identifier.issn/e-issn | 1302-7808;1308-5387 | |