Tandem aza-Michael additions under high pressure: a shortcut to the azanorbornyl skeleton
Tarih
JUN 52006
Yazar
Rulev, AY; Yenil, N; Pesquet, A; Oulyadi, H; Maddaluno, J
Üst veri
Tüm öğe kaydını gösterÖzet
The hyperbaric aza-Michael addition of mono- and diamines on alpha,beta-unsaturated beta,beta-disubstituted mono- and diesters has been studied. While in the case of monoester, this reaction provides a beta-aminoester presenting a quaternary center, a direct and efficient access to diester or lactams featuring an azanorbornyl skeleton was obtained when starting from a diester, following an unprecedented double aza-Michael addition. (c) 2006 Elsevier Ltd. All rights reserved.
Koleksiyonlar
- Web Of Science [8594]